A third person has been charged with murdering four children killed in a house fire in Salford on Monday.
David Worrall, 25, of Worsley, Salford, will appear before magistrates later and has also been charged with arson and attempted murder.
Zac Bolland, 23, and Courtney Brierley, 20, also from Worsley, are due before Manchester Crown Court on similar charges.
Four siblings aged three to 15 died as a result of the blaze.
Demi Pearson, 15, died at the scene on Jackson Street. Her brother and sister, Brandon, eight, and Lacie, seven, died later in hospital.
Three-year-old sister Lia died in hospital on Wednesday.
Their mother Michelle, 35, remains under sedation.
Two 16-year-olds, who cannot be named for legal reasons, managed to escape the blaze which broke out at about 05:00 GMT.
Mr Worrall, Mr Bolland and Ms Brierley have all been remanded in custody.
Greater Manchester Police has referred the case to the Independent Police Complaints Commission (IPCC) after confirming there had been incidents at the family's home prior to the fire.